How basal are triple-negative breast cancers?
نویسندگان
چکیده
منابع مشابه
Are triple-negative and basal-like breast cancer synonymous?
To the Editor: In a recent issue of Clinical Cancer Research, Dent and colleagues (1) have reported on the prognostic significance of estrogen negative, progesterone negative, and HER2 negative (triple-negative) class in a large cohort of breast cancer patients. Triple-negative tumors are undeniably one of the most relevant subgroups of breast cancer from a medical oncologist’s perspective, giv...
متن کاملCorrection: triple-negative, basal-like, and quintuple-negative breast cancers: better prediction model for survival
Correction After the publication of this work [1], we found that there were some mistakes in calculating the percentage of composition in Table 1 (1). Clinicopathologic characteristics of breast cancer subtypes. We are therefore providing the revised Table 1, with the updated data for rows ‘Mucinous carcinoma’, ‘Metaplastic carcinoma’ and ‘Others’. In the sub-content of Table 1, ‘Histological t...
متن کاملThe omics of triple-negative breast cancers.
BACKGROUND Triple-negative breast cancers (TNBC) do not represent a single disease subgroup and are often aggressive breast cancers with poor prognoses. Unlike estrogen/progesterone receptor and HER2 (human epidermal growth factor receptor 2) breast cancers, which are responsive to targeted treatments, there is no effective targeted therapy for TNBC, although approximately 50% of patients respo...
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grade (severity). Identification of molecular markers such as expression of the estrogen (er) and progesterone receptors (pgr) and the human epidermal growth factor receptor 2 (her2) has offered additional predictive value for the therapeutic assessment of women diagnosed with breast cancer 1–4. More recently, gene expression analysis using dna microarray technology has identified additional br...
متن کاملMolecular stratification of triple-negative breast cancers.
Research focused on the analysis and classification of breast tumors, primarily using DNA microarrays and patterns of gene expression, has resulted in distinct tumor subtypes. Although no knowledge of patient survival or outcomes was used to derive these gene descriptions, these different classes based upon patterns of gene expression have important prognostic implications. Predictive markers i...
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 2008
ISSN: 0020-7136,1097-0215
DOI: 10.1002/ijc.23518